Saturday, May 10, 2025

James Donaldson on Mental Health - The association between loneliness, suicidal ideation, and psychological distress considering family compositions: a cross-sectional study in a Japanese rural area

James Donaldson on Mental Health - The association between loneliness, suicidal ideation, and psychological distress considering family compositions: a cross-sectional study in a Japanese rural area

- Atsushi Iwasawa
- Fumiya Tanji
- Syohei Miyamoto & 
- Kyoko Nomura 

Abstract


Research on how loneliness, as a subjective experience, affects suicide risk remains insufficient. It also remains unclear whether the effects vary according to family composition. This study aimed to investigate the associations among loneliness, suicidal ideation, and psychological distress in a rural population in Japan. A cross-sectional survey was conducted between August and September 2023 in a rural town in Akita Prefecture. Of the 5,000 surveyed residents, data from 1,842 respondents were analyzed. The exposure variable was loneliness, as assessed by the University of California Los Angeles Loneliness Scale short form. The main outcome was the presence or absence of suicidal ideation, which was measured using a self-reported questionnaire. The secondary outcome was psychological distress, which was measured using the Kessler Psychological Distress Scale (K6). The collected data were analyzed using multivariate logistic regression and stratified analysis based on family composition. Loneliness was strongly associated with suicidal ideation and psychological distress. The loneliness–psychological distress association persisted regardless of family composition. Loneliness independently affected suicidal ideation and psychological distress among rural residents in Japan. To develop effective suicide prevention strategies in rural areas, it is essential to address both social isolation and the subjective experience of loneliness.


Introduction


Suicide is a serious global problem1. Numerous epidemiological studies have identified various risk factors for suicide, including a history of suicide attempts, family history of suicide, depression, social isolation, disasters, physical illness, and economic hardship2,3,4,5,6,7,8. Despite these advances, identifying clear causal pathways for suicide mechanisms remains a significant challenge. This has not prevented, nevertheless, several suicide prevention theoretical models and guidelines being proposed. Among these, the interpersonal theory of suicide, which explains that suicidal ideation arises when individuals simultaneously experience perceived burdensomeness and thwarted belongingness, has gained prominence in recent years9. Suicidal ideation occurs at an early stage of the progression of suicide attempts and completed suicides, is critical for such progression10,11, and reflects the emergence of psychological distress that can escalate if not intervened against. These characteristics render the construct an important indicator of suicide risk. Importantly, suicide results from the complex interplay of multiple factors12, making it such that prevention is key for effectively addressing both the personal and social factors related to suicide13.


Loneliness and social isolation are recognized as global problems and are associated with adverse mental health outcomes, such as depression14,15. They also heighten the risk of morbidity and mortality from chronic diseases16; therefore, they are regarded as critical targets for intervention in mental and public health. In recent years, loneliness and social isolation have also become pressing concerns in Japan. For example, from 2005 to 2020, the number of single-person households increased by six million (accounting for 40% of all households nationally)17, raising concerns about the potential decline in interactions among residents. This becomes even more paramount if we consider the concomitant phenomena in Japan of the shrinking population, falling birthrates, and aging society18. Since the enactment of the Basic Act on Suicide Countermeasures in 2006, the national government has implemented specific suicide prevention policies addressing social issues such as unemployment and economic hardships19. However, loneliness has often been overlooked as a critical factor in this context.


Japan has a higher suicide rate than other countries20, but the national suicide prevention efforts conducted over the past decade have gradually reduced suicide rates. Despite these attempts, suicide rates have recently increased among women and younger populations, indicating a demographic shift in suicidal tendencies at the national level21. One factor contributing to this shift in trends is that, beyond economic factors alone, reduced social interactions have exacerbated feelings of loneliness, leading to an increase in the number of suicides22. Additionally, a large Japanese study suggested loneliness as a significant factor contributing to the increased risk of suicide during the COVID-19 pandemic23.


Although often perceived as synonymous, loneliness and social isolation are distinct concepts. The first refers to a subjective sense of distress that occurs when social connections are perceived as inadequate/unfulfilling, whereas the latter is an objective indicator of estrangement in which social connections are limited or absent24,25,26. Therefore, the two concepts often conflate but do not always co-occur, in that isolated individuals may not feel lonely and those with abundant social connections can still experience loneliness27,28. Furthermore, although living alone has been suggested as a risk factor for suicide in previous studies29,30, there is data from a 2022 Japanese report showing that approximately two-thirds of suicide victims lived with others at the time of death (number of suicides among people not living alone, 14,266 vs. living alone, 7,414)31. In another study, individuals living only with their parents were found to have a higher risk of suicide32.


Previous research on suicide prevention in rural areas has often focused on older adults, who are particularly vulnerable to loss and social isolation33,34. The past literature has also reported on a link between living alone and depression among older adults35, but there is also importance in focusing on loneliness as a key factor in mental health and suicide prevention36. Based on previous studies, we hypothesize that loneliness has an independent influence on suicidal ideation and psychological distress, irrespective of family composition. This study aims to examine the association between loneliness, suicidal ideation, and psychological distress in Japanese rural residents. Rural towns in Japan face unique challenges that make them critical settings for studying loneliness and suicide prevention. These areas are characterized by significant population aging, which may be associated with increased loneliness and social isolation. Additionally, rural towns often have limited resources for mental health care and community support, emphasizing the need for practical and sustainable interventions suited to their specific circumstances. The results of this study have implications for the development of effective measures to address loneliness and social isolation, which may contribute to suicide prevention efforts in rural areas of Japan.


#James Donaldson notes:
Welcome to the “next chapter” of my life… being a voice and an advocate for #mentalhealthawarenessandsuicideprevention, especially pertaining to our younger generation of students and student-athletes.
Getting men to speak up and reach out for help and assistance is one of my passions. Us men need to not suffer in silence or drown our sorrows in alcohol, hang out at bars and strip joints, or get involved with drug use.
Having gone through a recent bout of #depression and #suicidalthoughts myself, I realize now, that I can make a huge difference in the lives of so many by sharing my story, and by sharing various resources I come across as I work in this space.
  #http://bit.ly/JamesMentalHealthArticle
Find out more about the work I do on my 501c3 non-profit foundation
website www.yourgiftoflife.org Order your copy of James Donaldson's latest book,
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Materials and methods


Study design and data collection

Akita Prefecture is one of the most rapidly aging prefectures in Japan, with a higher proportion of older adult residents compared to other regions. It also had the highest suicide rate among Japan’s 47 prefectures over the past two decades17,37. The suicide mortality rate varies significantly among the 25 municipalities within Akita Prefecture, with rural areas generally exhibiting higher rates than urban areas. Nearly half of the suicide victims in Akita Prefecture, are aged 60 years or older, indicating that addressing older adult suicides is a key concern in these regions37. Suicide prevention measures designed to address the characteristics of rural areas, including aging populations and higher suicide rates, are considered essential for reducing the overall suicide mortality in Akita.


Akita has a history of implementing suicide prevention initiatives, with municipalities organizing mental health lectures and other community-based interventions38,39. Addressing factors such as social isolation and loneliness in rural areas is anticipated to contribute to lowering suicide rates across the prefecture.


This cross-sectional study was based on a mental health survey conducted between August and September 2023 among residents aged 20 to 84 years in a rural town in Akita Prefecture, northern Japan. The town had approximately 14,000 residents at the time of the survey. In Japan, all prefectures and municipalities are required to develop regional suicide prevention plans tailored to the local context. This survey was conducted to develop suicide countermeasures for rural populations based on Japan’s General Principles of Suicide Countermeasures Policy40. The prevalence of suicidal ideation in Akita Prefecture has been estimated to be approximately 3.7%37. To ascertain the prevalence of suicidal ideation with an accuracy of 3.7% and a 1% margin of error, the required sample size was 2028. Assuming a response rate of approximately 40%, the sample size was set to 5000. Using stratified random sampling based on sex and age distribution, 5000 residents aged 20 to 84 were selected from a population of approximately 14,000. Sampling was conducted using the basic resident register managed by the municipality. This register contains information about one’s date of birth, sex, and address.


This survey will serve as a baseline survey for formulating countermeasure plans, with a follow-up survey scheduled for 2025 to assess longitudinal trends. The purpose of the survey was explained in the town’s public newsletter to ensure the smooth distribution of the questionnaires. It was also announced that all personal information necessary for follow-up surveys would be managed by the local government. The extraction of participant addresses and the management of personal information were handled by public health nurses from the municipality, who also led the coordination and announcement process in the town’s public newsletter. We excluded individuals certified as support level 2 or higher under the Japanese Long-Term Care Insurance (LTCI) system, as these individuals had functional disabilities that could hinder independent survey completion.


Anonymous questionnaires were mailed to 5,000 residents between August and September 2023. Returning a completed questionnaire was considered a consent to participate in the study; an explanation of the research purpose was provided alongside the survey. Participants were also informed about a follow-up survey scheduled for 2025 and their right to withdraw consent. Those wishing to withdraw consent by December 2023 could do so by submitting a withdrawal letter or answering a Google Form. Individuals who withdrew consent were excluded from the analysis, and measures were taken to ensure they would not receive the follow-up survey.


The questionnaire included items on demographic characteristics, loneliness, suicidal ideation, and psychological distress. This study followed the STROBE guidelines for reporting observational studies41.


Measures

Sex was classified as male or female. Age was categorized into three groups: 20–39 years, 40–59 years, and ??60 years. Family composition was defined as either living alone or living in a household with multiple occupants. Marital status was grouped into never married, married, separated, widowed, or missing. Subjective economic status was assessed on a five-point scale ranging from good to poor, or missing. Medical history was categorized into four groups: disease-free, having physical health conditions, having mental health conditions, multimorbidity (physical and mental health conditions), or missing.


Self-reported loneliness was the exposure variable. Loneliness was measured using the six-item University of California, Los Angeles (UCLA) Loneliness Scale (ver. 3), a loneliness scale developed by Russel42. We specifically used its six-item short form, which has been validated in Japanese by Toyoshima and Sato43. Items were responded to on a four-point scale, with total scores ranging from 0 to 24 and being calculated by summing the scores of all items. As there was no established cut-off point for this scale, we followed prior studies and distinguished the presence of loneliness based on the upper quartile of the distribution44. That is, a score in the third quartile or above (UCLA score???15) was defined as experiencing loneliness, and a binary variable was created to classify loneliness presence or absence.


The outcome variables were suicidal ideation and psychological distress, both of which were self-reported. Suicidal ideation was measured using the following question, “Did you think about committing suicide in the past month?” To which participants responded with “yes,” “no,” or “unsure,” with a “yes” answer representing that the respondent experienced suicidal ideation. Since suicidal ideation precedes suicide attempts or completion10,11, it can be regarded as a key predictor of suicide risk. This study used only this single-item to measure this construct in an attempt to simultaneously deal with the ethical concerns surrounding studies on suicide and to promote ease of response for participants. We aimed to minimize the number of questions on suicide while focusing on identifying “suicidal ideation,” which is considered essential for implementing effective interventions. The item used in this survey was adapted from the Ministry of Health, Labour and Welfare’s 2021 Survey on Attitudes Toward Suicide Countermeasures45.


Psychological distress was measured using the Kessler Psychological Distress Scale (K6), a six-item questionnaire that evaluates mood and anxiety experienced in the last 30 days46. The total K6 scores ranged from 0 to 24.

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